← Back to brief
Sanz Solutions logo

Sanz Solutions

Concierge pharmacy

Playbook

Asthma

Clinical guide · patient + provider

Asthma

Audience: Patients and providers
Status: Clinical guide · patient + provider
Last updated: 2026-03-09


1. Clinical overview

Asthma is a chronic inflammatory airway disorder with variable bronchoconstriction, symptom fluctuation, and exacerbation risk that depends heavily on trigger control, adherence, and inhaler technique.

2. Common causes and risk factors

  • Chronic inflammatory airway disease with variable airflow obstruction.
  • Triggers include allergens, viral infections, irritants, exercise, reflux, and poor adherence.

3. Typical symptoms

  • Wheeze, cough, chest tightness, nighttime symptoms, activity limitation.

4. Diagnosis and evaluation

  • Confirm diagnosis with guideline-based history, exam, and indicated testing.
  • Screen for severity, complications, and high-risk comorbid conditions.
  • Identify social or access barriers that could affect treatment success.

5. Treatment (non-pharmacologic)

  • Trigger reduction and comorbidity management (rhinitis, GERD, obesity).
  • Written asthma action plan and spacer/technique training.
  • Vaccination and smoking/vaping cessation support.

6. Treatment (pharmacologic)

  • ICS-containing therapy is core, with common options including budesonide, fluticasone, or mometasone-based inhalers.
  • SMART regimens commonly use budesonide/formoterol, while step-up maintenance therapy may include fluticasone/salmeterol or fluticasone/umeclidinium/vilanterol in selected severe disease.
  • Biologics such as omalizumab, dupilumab, mepolizumab, benralizumab, or tezepelumab are reserved for phenotype-guided severe asthma.

7. Monitoring and follow-up

  • Control scores, rescue use, exacerbations, lung function, adherence and inhaler technique.

8. Practical counseling points

  • Give patients a clear “what to do today / when to call / when to seek urgent care” plan.
  • Use teach-back to confirm understanding of treatment goals and medication instructions.
  • Simplify regimens when possible to improve adherence and outcomes.

9. Red flags and escalation

  • Escalate care urgently for severe or rapidly worsening symptoms.
  • Reassess diagnosis if expected response does not occur within the anticipated timeline.

10. Guideline references


Note: Educational guide only; not a substitute for individualized medical care.

Next step

Grab the full medication cost-savings toolkit with ready-to-use checklists and guides.

Download the toolkit →