← Back to brief
Sanz Solutions logo

Sanz Solutions

Concierge pharmacy

Playbook

Cellulitis guide

Clinical guide · patient + provider

Cellulitis Guide

What it is

Cellulitis is a bacterial skin and soft tissue infection, typically involving erythema, warmth, swelling, and tenderness.

Common causes

  • Beta-hemolytic streptococci
  • Staphylococcus aureus (including MRSA in selected risk profiles)

Treatment approach

  • Mild/moderate non-purulent infection: oral beta-lactam pathways in appropriate patients.
  • Purulent or MRSA-risk infection: MRSA-active oral options with source control when needed.

Non-pharmacologic care

  • Elevation of affected limb
  • Wound/skin care and edema control
  • Foot care education in diabetes

Monitoring and follow-up

  • Mark borders to track response over 24-48 hours
  • Escalate for fever, rapid progression, systemic symptoms, or treatment failure

Guideline references

Next step

Grab the full medication cost-savings toolkit with ready-to-use checklists and guides.

Download the toolkit →