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Nonalcoholic fatty liver disease guide

Clinical guide · patient + provider

Nonalcoholic Fatty Liver Disease Guide

What it is

Nonalcoholic fatty liver disease (NAFLD/MASLD terminology in evolving use) is excess hepatic fat not primarily due to alcohol.

Risk context

  • Obesity
  • Type 2 diabetes
  • Dyslipidemia
  • Metabolic syndrome

Treatment approach

  • Weight-loss centered lifestyle intervention
  • Cardiometabolic risk factor optimization
  • Specialist referral based on fibrosis risk stratification

Non-pharmacologic care

  • Calorie-deficit nutrition plan with sustainable adherence
  • Physical activity progression
  • Alcohol moderation counseling

Monitoring and follow-up

  • Liver enzyme trends, fibrosis risk scores, and metabolic marker control

Guideline references

Next step

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