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Sanz Solutions

Concierge pharmacy

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Peripheral artery disease guide

Clinical guide · patient + provider

Peripheral artery disease guide

Snapshot

  • Typical symptoms: Exertional calf/thigh pain, reduced walking distance, delayed wound healing.
  • High-risk profile: Diabetes, tobacco use, CKD, hypertension, hyperlipidemia.

Initial workup

  • Resting ABI for suspected PAD.
  • Pulse exam, skin/foot exam, ulcer assessment.
  • Consider vascular referral for severe symptoms, rest pain, or tissue loss.

Treatment priorities

  1. Antiplatelet therapy when indicated.
  2. High-intensity statin unless contraindicated.
  3. Optimize BP, glucose, and tobacco cessation.
  4. Structured walking program and supervised exercise when available.

Escalation triggers

  • Rest pain, non-healing ulcers, gangrene, rapidly declining function.
  • ABI decline with worsening symptoms.

Follow-up cadence

  • Reassess walking tolerance, wound status, med adherence, and smoking status every 4–12 weeks during active management.

Next step

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